The Role of Preimplantation Genetic Diagnosis (PGD) in IVF: What You Need to Know

For couples carrying hereditary genetic mutations, planning a family involves protecting future generations from passing down these conditions. Unsuccessful natural cycles or worries about passing down disorders can make conception stressful. However, advanced embryology offers a highly precise solution: preimplantation genetic diagnosis PGD (also known as PGT-M for monogenic disorders) to screen embryos for specific single-gene conditions before transfer.

This comprehensive guide details how genetic screening is performed in the laboratory, compares PGD and PGS, and explains its role in ensuring a healthy pregnancy.

PGD, PGS, and Embryo Health

PGD checks single-gene mutations. It differs from PGS/PGT-A screening (read details in our PGT-A testing guide). Implantation rates are optimized (details in our successful implantation guide) using graded blastocysts (read details in our embryo grading guide). Check cost tips in our Delhi IVF cost guide.

Protect Your Future Family's Health
Screening embryos for single-gene disorders is the most effective way to prevent passing down hereditary conditions. If you want to check your genetic screening options or discuss customized DNA probes, you can schedule a genetic consultation at Pravi Global IVF.

PGD in IVF Frequently Asked Questions (FAQ)

1. Does removing cells from the embryo damage it?
No, extracting 5-10 outer cells from a day-5 trophectoderm is safe for embryogenesis.

2. How long does it take to get PGD results?
The DNA analysis typically requires 2 to 3 weeks during which embryos remain frozen.

3. Can PGD screen for all genetic diseases?
It can screen for any monogenic condition once the parents' mutation is identified.

4. What is the cost of PGD in India?
Custom probe design and NGS test typically costs Rs. 25,000 to Rs. 45,000 per embryo.

5. What happens to the embryos that carry the mutation?
Mutation-carrying embryos are not selected for transfer and are managed based on parent choice.

Conclusion

Using **preimplantation genetic diagnosis PGD** prevents passing down severe hereditary conditions. Our lab offers molecular genetics. Contact Pravi Global IVF today to schedule your evaluation.