PGT Testing in Delhi
Preimplantation Genetic Testing — PGT-A, PGT-M & PGT-SR
At Pravi IVF in Lajpat Nagar, Delhi, we offer the full spectrum of PGT — the globally standardised approach to embryo genetic screening. By testing your embryos before implantation, we help you achieve a healthy pregnancy with confidence.
What is PGT? The Complete Guide
Preimplantation Genetic Testing (PGT) is a sophisticated diagnostic technique performed on embryos created through IVF (In Vitro Fertilisation) before they are transferred into the uterus. The overarching goal is simple yet profound: to identify which embryos are free of chromosomal abnormalities or specific genetic disorders, giving every transfer the best possible chance of resulting in a healthy, full-term pregnancy.
The term PGT is the modern, globally unified terminology endorsed by leading reproductive bodies including ESHRE (European Society of Human Reproduction and Embryology) and ASRM (American Society for Reproductive Medicine). It encompasses three distinct sub-types — PGT-A, PGT-M, and PGT-SR — each targeting a different category of genetic risk. At Pravi IVF, Lajpat Nagar, Delhi, our genetics team offers all three, tailored precisely to your clinical history.
The Three Types of PGT Explained
PGT-A (Aneuploidy Testing)(Formerly PGS)
Screens all 24 chromosomes for numerical abnormalities (extra or missing chromosomes). Ideal for advanced maternal age, recurrent implantation failure, and repeated miscarriages to dramatically reduce miscarriage risk.
PGT-M (Monogenic/Single-Gene Disorders)(Formerly PGD)
Tests embryos for specific inherited single-gene conditions like Thalassemia, Cystic Fibrosis, or Sickle Cell Anaemia. Personalized molecular probes are built per family to prevent passing hereditary conditions down.
PGT-SR (Structural Rearrangements)
Detects unbalanced chromosomal structural rearrangements (such as translocations or inversions) in parents who are known carriers, reducing recurrent pregnancy loss and failed transfer cycles.
Who Should Consider PGT?
While PGT can benefit any IVF patient, certain clinical profiles make it especially valuable. Our specialists at Pravi IVF will review your history and recommend the most appropriate PGT type during your consultation, particularly for:
The PGT Process — Step by Step at Pravi IVF
Ovarian Stimulation & Egg Retrieval
The cycle begins with hormone stimulation to produce multiple eggs, which are then retrieved in a minimally invasive, painless day-care procedure.
Fertilisation via ICSI
Each mature egg is fertilised using ICSI (Intracytoplasmic Sperm Injection) to create embryos with maximum efficiency in our state-of-the-art laboratory.
Blastocyst Culture (Day 5-6)
Embryos are cultured in advanced benchtop incubators for 5-6 days until they reach the blastocyst stage — the optimal multicellular point for a safe biopsy.
Trophectoderm Biopsy
Our expert embryologists perform a laser-assisted microsurgical biopsy, removing 3-5 cells from the outer layer (trophectoderm) which goes on to form the placenta, without harming the inner cell mass (the baby).
Next-Generation Sequencing (NGS)
Biopsied cells undergo advanced NGS analysis in a certified genetics lab, mapping the complete chromosomal and/or genetic profile with near-perfect 99% accuracy.
Embryo Selection & Frozen Transfer
Our clinicians review the genetic report, select the healthiest euploid (chromosomally normal) embryo, and proceed with a prepared frozen embryo transfer (FET) for the best outcome.
Why PGT is Redefining Fertility Success in Delhi
The Hidden Cause of IVF Failure: Chromosomal Aneuploidy
Studies consistently show that chromosomal aneuploidy — an incorrect number of chromosomes — is the single largest cause of IVF failure and early miscarriage. Alarmingly, a morphologically "perfect-looking" blastocyst can still harbour a silent chromosomal error invisible to the naked eye or standard microscopy. PGT-A eliminates this uncertainty by providing a definitive genetic passport for each embryo before transfer, dramatically improving the per-transfer success rate.
Protecting Future Generations with PGT-M
For families carrying the weight of heritable diseases — Thalassemia, Sickle Cell Anaemia, Cystic Fibrosis, Spinal Muscular Atrophy, Huntington's Disease, and more — PGT-M offers a compassionate solution. By testing embryos before implantation, couples can break the cycle of genetic disease, selecting only those embryos that have not inherited the condition. Our genetics team at Pravi IVF designs a bespoke molecular probe for your specific mutation, ensuring the highest diagnostic precision.
The Role of Next-Generation Sequencing (NGS) in PGT
Pravi IVF leverages Next-Generation Sequencing — the gold standard in genomic analysis — for all PGT testing. NGS simultaneously reads millions of DNA fragments, providing near-perfect resolution across all 24 chromosome types. This supersedes older array-CGH and FISH methods, offering greater sensitivity to detect even mosaic embryos (those with a mixture of normal and abnormal cells). With NGS, you can trust that the report reflects the most accurate picture of your embryo's genetic health currently available in medical science.
Reducing Costs and Emotional Burden of IVF Cycles
While PGT adds a one-time cost, the investment often pays for itself by reducing the number of failed transfers. Each failed cycle carries emotional distress, recovery time, and additional medical expenses. By transferring only the embryo most likely to succeed, PGT reduces the average number of cycles needed to achieve a live birth — making your overall IVF journey more efficient, less stressful, and ultimately more cost-effective.
Book Consult
Schedule a baseline diagnostic consult with our senior reproductive geneticists and embryologists.
Book Free ConsultationCall Genetics LabBiopsy Integrity
- 100% safety record with laser-assisted Day 5 blastocyst trophectoderm biopsy.
- Advanced cryo-vitrification preserving embryos at -196°C with zero tissue decay.
- Certified genetic counselors mapping karyotypes with empathy and transparency.
- Full ICMR legal guidelines compliance for genetic diagnostics.
Frequently Asked Questions About PGT
QWhat is PGT and how is it different from PGS/PGD?
PGT (Preimplantation Genetic Testing) is the current, unified umbrella term endorsed by reproductive medicine bodies worldwide. PGT-A replaces the older term PGS (screening for aneuploidy/chromosome counts), PGT-M replaces PGD (screening for specific single-gene inherited diseases), and PGT-SR covers structural rearrangements. The science is the same—the updated naming simply brings global standardisation.
QIs the embryo biopsy procedure safe?
Yes. Biopsy is performed at the blastocyst stage (Day 5-6), when the embryo has over 100 cells. Removing just 3-5 cells from the trophectoderm (future placenta) using an ultra-precise laser is clinically proven safe and does not impact the embryo's ability to develop into a healthy baby.
QHow long do PGT results take?
Genetic analysis typically takes 7-14 days. During this time, the embryos are safely vitrified (fast-frozen) in our advanced liquid nitrogen storage tanks. A frozen embryo transfer (FET) cycle is then planned and scheduled once results are available.
QDoes PGT guarantee a healthy baby?
PGT significantly reduces chromosomal and genetic risks, carrying a diagnostic accuracy of over 99%. While no medical test can carry a 100% guarantee, PGT gives you the best scientific evidence to make an informed decision and maximises your probability of a healthy live birth.
QWhat is the cost of PGT in Delhi?
Pricing depends on the type of PGT required (PGT-A, PGT-M, or PGT-SR) and the number of embryos being tested. Please contact our team for a transparent, personalised cost estimate with no hidden charges.
Give Your Embryo the Genetic Advantage
Don't leave your IVF outcome to chance. Book a PGT consultation at Pravi IVF, Lajpat Nagar, Delhi and let science guide you to a healthier pregnancy.
